Everything you need to know about study requirements and sites open for enrollment
Loyal’s latest milestone: the first longevity clinical study design supported by the FDA
At Loyal we’re developing the first FDA-approved drugs explicitly intended to extend lifespan and healthspan, and being first means charting new waters.
On the path to FDA approval, we must run a clinical trial that objectively and robustly demonstrates that our drug extends dogs’ healthy lifespan, and does so safely. Because no one has developed a dog — or human — longevity drug before, we are building the path to FDA approval largely from scratch.
Last week we learned from the FDA that Loyal received protocol concurrence for our companion dog longevity study — likely the first time the FDA has given their blessing to a longevity clinical trial. Our regulatory expert Karen Greenwood weighs in on what this means for Loyal, for the field of aging, and for dogs everywhere.
How scientists measure aging through Healthspan, frailty and quality of life
Our Healthspan study results have been published in GeroScience. Let’s dive into the results.
How old is your dog, really? Predicting age through methylation
We know biological samples can tell us about our dog’s health and breed ancestry, but is the saliva in your dog’s mouth enough to tell us your dog’s age and birthday? The answer is, in some ways, yes.
Why do big dogs have unusually short lifespans compared to small dogs?
Dogs come in an astounding range of shapes and sizes. Explore how genetic differences impact age and how Loyal is working on extending the lives and health of large dogs.
New in dog health: Sniffing out this month’s discoveries in science
Do dogs “see” with their noses? Can my dog feel guilt? Can dogs catch monkeypox from their owners? Find out in this month’s review on canine science research.
The Canine 39: An encyclopedia of your dog’s genome
An average-sized dog may have 10 trillion cells in its body. If you stretched all the DNA in these cells end to end, how far would it reach?
Clinical trials in the real world: One practitioner’s perspective
Why I’d love to see general practitioners participate in clinical research: 5 compelling reasons from a former GP
Introducing X-Thousand Dogs
The largest study of its kind, aimed at better understanding how dogs age—and how we might help them live longer, healthier lives