Our mission is to help dogs everywhere live longer, healthier lives.
Loyal is a clinical-stage veterinary medicine company developing drugs intended to extend the healthspan and lifespan of dogs.
Cellular Longevity
We’re part of Cellular Longevity, a San Francisco-based biotech firm leading pioneering research into the science of longevity.
Learn more
Leadership team
Andrew Bredow
Director,
Engineering
Brennen McKenzie
Director,
Veterinary Medicine
Celine Halioua
Founder & CEO
Dina Juarez-Salinas
Vice President,
Preclinical Development
Ellen Ratcliff
Director,
Clinical Development
John Poisson
Executive Creative Director
Karen Greenwood
Senior Vice President,
Regulatory & Strategy
Lauren Knight
Director,
Operations
Stacy Ross
Vice President,
Drug Development
Sahba Sabeti
Director,
Marketing
Stefan Leape
Chief of Staff
Sudharika Gogna
Chief Operating Officer
Tony Gonzalez
Director,
Analytical Chemistry
Venkata Adapala
Director,
Clinical Operations
Board of Directors
Blake Scholl
Independent Director,
Founder & CEO, Boom Supersonic
Celine Halioua
Common Director,
Founder/CEO
Greg Rosen
Board Observer,
Box Group
Josh Kopelman
Board Observer,
First Round Capital
Laura Deming
Common Director,
Founder/GP Longevity Fund
Dr. Stephen Betz
Board Observer,
Founder & CSO, Crinetics Pharmaceutics
Our team
152
Papers published
56
Clinical drug programs worked on
192
Years of research
62%
Women
Backed by the best
Our mission is supported by world-class funds and investors.
Our values
Lean into moonshots
We don’t settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have.
Opportunity is at the intersection
We lean into combining disciplines, expertise, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos.
Expertise without ego
Titles do not determine who has a voice. We work on hard, technical problems and have a ton of fun while at it.
Learn by doing
Our path is novel and many things we’re doing have never been done before. We lean into MVPs and are open to unexpected outcomes.
Lead with context
We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. Empower team to succeed.
Empathy and respect for all life
Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.
Loyal in the news
New York Times
Nov 28, 2023
Could a Drug Give Your Pet More Dog Years?
Wired
Nov 28, 2023
A Life-Extension Drug for Big Dogs Is Getting Closer to Reality
Business Insider
Nov 28, 2023
Longevity Drug For Dogs Moves Closer to FDA Approval
The Telegraph
Oct 21, 2023
Dogs could have lifespan extended with promising new drug
CBS Saturday Morning
Oct 14, 2023
Researchers work to increase the lifespan of pets
BBC Radio
Sep 4, 2023
The Immortals — Ep 5: The Trial
This Week in Startups
Aug 31, 2023
Developing drugs to extend dog lifespans with Loyal CEO Celine Halioua
Axios
Aug 17, 2023
Startup is developing a pill intended to help large dogs live longer
Fox Interviewer
Aug 23, 2023
40 Under 40, #21: Celine Halioua
Wired
Jun 28, 2023
A Dog's Life Could Hold the Key to Anti-Aging Drugs for Humans
Danny in the Valley
May 4, 2023
Loyal’s Celine Halioua: “The first life extension drug for dogs”
San Francisco Business Times
April 21, 2023
40 Under 40: Celine Halioua, Loyal
Explain it to me like I’m a 10 year old
March 19, 2023
Ep.52: Being Loyal to Our Dogs, with Celine Halioua
Forbes
March 10, 2023
This 30 Under 30 Alumna Is One Step Closer To Helping Your Dogs Live Longer
Longevity.Technology
March 10, 2023
First longevity clinical study design fetches FDA approval
ABC 7 News
February 3, 2023
More time with your pets? SF biotech company trying to create fountain of youth for dogs
KFI AM 640
January 25, 2023
Is There A Fountain of Youth For Dogs?
Popular Mechanics
January 17, 2023
Scientists Are Testing a Pill to Make Dogs Stop Aging
San Francisco Chronicle
January 16, 2023
A fountain of youth for dogs? This S.F. startup says it’s on the way
The Problem With Jon Stewart Podcast
November 30, 2022
The CEO in Search Of The Fountain Of Youth…For Dogs
Axios
November 30, 2022
Biotech startup predicts age of dogs in hunt for clues about human aging
Wired
October 13, 2022
The Search for a Pill That Can Help Dogs—and Humans—Live Longer
iHeartDogs
October 19, 2022
Two “Magic Pills” To Extend Your Dog’s Life Are On The Way
MIT Technology Review
August 15, 2022
These scientists are working to extend the lifespan of pet dogs – and their owners
The New Statesman
August 6, 2022
Do you want to live forever? Big Tech and the quest for eternal youth
Freethink (Heretics)
June 23, 2022
“I work on dog lifespan extension.” | Celine Halioua for Heretics
Huge If True
May 18, 2022
Why your dog isn’t the age you think
Forbes
December 8, 2021
Inside the 30 Under 30 List
FierceBioTech
November 23, 2021
Founder-led biotech is making space for ideas– and diverse leaders– where it didn’t exist before
TechCrunch
September 23, 2021
Loyal raises $27M, aims to give dog owners more time with their pets
San Francisco Business Times
July 6, 2021
Why this San Francisco anti-aging drug startup thinks it’s barking up the right tree
Veterinary Practice News
June 23, 2021
Canine cancer biomarkers to be explored
The Times
June 1, 2021
A dog’s life can be longer, promises tech start-up
The Hill
May 26, 2021
How Silicon Valley is helping dogs live longer– so humans can live longer too
Bloomberg
May 24, 2021
Silicon Valley Wants Dogs to Live Longer So Humans Can, Too
Announcements

March 21, 2024

Loyal Announces $45 Million Series B Financing to Continue Development of First FDA-Approved Dog Lifespan Extension Drug for Veterinary Use
Read article   

August 11, 2023

Announcing our partnership with Crinetics Pharmaceuticals
Read article   

March 10, 2023

Loyal’s latest milestone: the first longevity clinical study design supported by the FDA
Read article   

March 23, 2022

Loyal introduces the largest dog epigenetics study ever conducted
Read article   

September 2, 2021

Loyal completes its first clinical study
Read article   

September 1, 2021

Two Loyal-nominated compounds selected for the National Institute on Aging Interventions Testing Program
Read article   

August 2, 2021

Loyal in-licenses mouse-canine-human epigenetic clock from UCSD
Read article   

June 7, 2021

Morris Animal Foundation Partners with Loyal to Study Dogs’ Genetic Changes that Occur as They Age
Read article   
Publications
Frontiers
November, 2023
Body weight, gonadectomy, and other risk factors for diagnosis of osteoarthritis in companion dogs ->
Graves JL, McKenzie BA, Koch Z, Naka A, Spofford N, Morrison J. Body weight, gonadectomy, and other risk factors for diagnosis of osteoarthritis in companion dogs. Front. Vet. Sci. 2023 November 28; 10:1275964.
Topics in Companion Animal Medicine
November, 2022
Assessment and Management of Declining Physical Function in Aging Dogs ->
McKenzie B, Chen FL. Assessment and Management of Declining Physical Function in Aging Dogs. Topics in Companion Animal Medicine. 2022 Nov 13; 51:100732.
GeroScience
February, 2023
Evaluating instruments for assessing healthspan: a multi-center cross-sectional study on health-related quality of life (HRQL) and frailty in the companion dog ->
Chen FL, Ullal TV, Graves JL, Ratcliff ER, Naka A, McKenzie B, Carttar TA, Super KM, Austriaco J, Weber SY, Vaughn J, LaCroix-Fralish ML. Evaluating instruments for assessing healthspan: a multi-center cross-sectional study on health-related quality of life (HRQL) and frailty in the companion dog. GeroScience. 2023 Feb 13.
JNeurosci (The Journal of Neuroscience)
August, 2022
Extensive Connections of the Canine Olfactory Pathway Revealed by Tractography and Dissection ->
Andrews EF, Pascalau R, Horowitz A, Lawrence GM, Johnson PJ. Extensive Connections of the Canine Olfactory Pathway Revealed by Tractography and Dissection. J Neurosci. 2022 Aug 17;42(33):6392-407.
AVMA (American Veterinary Medical Association)
June, 2022
The phenotype of aging in the dog: how aging impacts the health and well-being of dogs and their caregivers ->
McKenzie BA, Chen FL, LaCroix-Fralish ML. The phenotype of aging in the dog: how aging impacts the health and well-being of dogs and their caregivers. AVMA. 2022 Jun 1;260(9):963-70.
AVMA (American Veterinary Medical Association)
June, 2022
Comparative veterinary geroscience: mechanism of molecular, cellular, and tissue aging in humans, laboratory animal models, and companion dogs and cats ->
McKenzie BA. Comparative veterinary geroscience: mechanism of molecular, cellular, and tissue aging in humans, laboratory animal models, and companion dogs and cats. AJVR. 2022 Jun 1;83(6).
Frontiers
April, 2022
Canine Geriatric Syndrome: A Framework for Advancing Research in Veterinary Geroscience ->
McKenzie BA, Chen FL, Gruen ME, Olby NJ. Canine Geriatric Syndrome: A Framework for Advancing Research in Veterinary Geroscience. Front. Vet. Sci. 2022 April 21;9:853743.
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