Our mission is to help dogs everywhere live longer, healthier lives.
Loyal is a clinical-stage veterinary medicine company developing drugs intended to extend the healthspan and lifespan of dogs.
Cellular Longevity
We’re part of Cellular Longevity, a San Francisco-based biotech firm leading pioneering research into the science of longevity.
Learn more
Leadership team
Celine Halioua
Founder & CEO
Claire Pickens
Vice President,
Veterinary Operations
Daniel Civello
Vice President,
Bioinformatics
Dina Juarez-Salinas
Vice President,
Preclinical Development
John Poisson
Chief Creative Officer
Karen Greenwood
Senior Vice President,
Regulatory & Strategy
Stacy Ross
Vice President,
Drug Development
Stefan Leape
Chief of Staff
Board of Directors
Celine Halioua
Common Director,
Founder/CEO
Laura Deming
Common Director,
Founder/GP Longevity Fund
Alex Morgan
Preferred Director,
Khosla Ventures
Josh Kopelman
Board Observer,
First Round Capital
Greg Rosen
Board Observer,
Box Group
Our team
152
Papers published
56
Clinical drug programs worked on
192
Years of research
54%
Women
Backed by the best
Our mission is supported by world-class funds and investors.
Announcements

March 23, 2022

Loyal introduces the largest dog epigenetics study ever conducted
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September 2, 2021

Loyal completes its first clinical study
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September 1, 2021

Two Loyal-nominated compounds selected for the National Institute on Aging Interventions Testing Program
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August 2, 2021

Loyal in-licenses mouse-canine-human epigenetic clock from UCSD
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June 7, 2021

Morris Animal Foundation Partners with Loyal to Study Dogs’ Genetic Changes that Occur as They Age
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Publications
JNeurosci (The Journal of Neuroscience)
August, 2022
Extensive Connections of the Canine Olfactory Pathway Revealed by Tractography and Dissection ->
Andrews EF, Pascalau R, Horowitz A, Lawrence GM, Johnson PJ. Extensive Connections of the Canine Olfactory Pathway Revealed by Tractography and Dissection. J Neurosci. 2022 Aug 17;42(33):6392-407.
Biorxiv
July, 2022
Evaluating instruments for assessing healthspan: a multi-center cross-sectional study on health-related quality of life (HRQL) and frailty in the companion dog ->
Chen FL, Ullal TV, Graves JL, Ratcliff ER, Naka A, McKenzie B, Carttar TA, Super KM, Austriaco J, Weber SY, LaCroix-Fralish ML. Evaluating instruments for assessing healthspan: a multi-center cross-sectional study on health-related quality of life (HRQL) and frailty in the companion dog. bioRxiv. 2022 Jul 21.
AVMA (American Veterinary Medical Association)
June, 2022
The phenotype of aging in the dog: how aging impacts the health and well-being of dogs and their caregivers ->
McKenzie BA, Chen FL, LaCroix-Fralish ML. The phenotype of aging in the dog: how aging impacts the health and well-being of dogs and their caregivers. AVMA. 2022 Jun 1;260(9):963-70.
AVMA (American Veterinary Medical Association)
June, 2022
Comparative veterinary geroscience: mechanism of molecular, cellular, and tissue aging in humans, laboratory animal models, and companion dogs and cats ->
McKenzie BA. Comparative veterinary geroscience: mechanism of molecular, cellular, and tissue aging in humans, laboratory animal models, and companion dogs and cats. AJVR. 2022 Jun 1;83(6).
Frontiers
April, 2022
Canine Geriatric Syndrome: A Framework for Advancing Research in Veterinary Geroscience ->
McKenzie BA, Chen FL, Gruen ME, Olby NJ. Canine Geriatric Syndrome: A Framework for Advancing Research in Veterinary Geroscience. Front. Vet. Sci. 2022 April 21;9:853743.
Nature
October, 2021
AdRoit is an accurate and robust method to infer complex transcriptome composition ->
Yang T, Alessandri-Haber N, Fury W, Schaner M, Breese R, LaCroix-Fralish ML, et al. AdRoit is an accurate and robust method to infer complex transcriptome composition. Commun Biol. 2021 Oct 22;4(1):1-4.
Frontiers
September, 2021
Advancing Genetic Selection and Behavioral Genomics of Working Dogs Through Collaborative Science ->
Chen FL, Zimmermann M, Hekman JP, Lord KA, Logan B, Russenberger J, et al. Advancing Genetic Selection and Behavioral Genomics of Working Dogs Through Collaborative Science. Front. Vet. Sci. 2021 Sept 6;8:662429.
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